Update on Genetics Research in Stuttering

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Re: MLII/MLIII and Stuttering

From: Dennis Drayna
Date: 17 Oct 2011
Time: 16:19:26 -0500
Remote Name: 165.112.47.66

Comments

Children with MLII are severely affected, and even those that live the longest (7-8 years) speak rarely if ever. Children with MLIII are less severely affected, and often live until young adulthood. They can have speech problems, but this is complicated by the fact that they often have broad developmental delay and disabilities, so their speech problems may be caused by other more general problems in the brain. People with MLII and MLIII generally have mutations that largely or completely eliminate the function of these genes. People who stutter have a different type of mutations, which seem to leave about 50% of the function of these genes.


Last changed: 10/17/11